Surgical Sciences

The Surgical Sciences Research Domain welcomes basic, translational or clinical projects dealing with diseases from the digestive, pulmonary and urogenital systems. Globally, all projects aim to find new strategies to minimize surgical aggression either in repairing (congenital disorders) or ablative/resection (malignant disorders) procedures.

 

ICVS

Surgical Sciences Publications

Expression of tyrosine kinase receptor AXL is associated with worse outcome of metastatic renal cell carcinomas treated with sunitinib

Zucca LE, Morini-Matushita M, Silva Oliveira R, Scapulatempo-Neto C, de Lima MA, Ribeiro GG, Viana CR, Cárcano FM, Reis RM. Expression of tyrosine kinase...

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Internalization Studies of Zeolite Nanoparticles using Human Cells

Vilaça N, Totovao R, Prasetyanto EA, Miranda-Gonçalves V, Morais-Santos F, Fernandes R, Figueiredo F, Bañobre-López M, Fonseca AM, De Cola L, Baltazar F...

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Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy

Tavares-Valente D, Granja S, Baltazar F, Queirós O. Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy. Journal of...

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A simple architecture with self-assembled monolayers to build immunosensors for detecting the pancreatic cancer biomarker CA19-9

Soares AC, Soares JC, Shimizu FM, Rodrigues VC, Awan IT, Melendez ME, Piazzetta MH, Gobbi ML, Reis RM, Fregnani JH, Carvalho AL, Oliveira ON. A simple...

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Microfluidic-Based Genosensor to Detect Human Papillomavirus (HPV16) for Head and Neck Cancer

Soares AC, Soares JC, Rodrigues VC, Follmann HDM, Arantes LMRB, Carvalho AC, Melendez ME, Fregnani JHTG, Reis RM, Carvalho AL, Oliveira ON. Microfluidic-Based...

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Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells

Silva VAO, Rosa M, Miranda-Gonçalves V, Costa AM, Tansini A, Evangelista AF, Martinho O, Carloni A, Jones C, Lima JP, Pianowski L, Reis RM. Euphol, a...

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Hexane partition from Annona crassiflora Mart. promotes cytotoxity and apoptosis on human cervical cancer cell lines

Silva VAO, Alves AL, Rosa MN, Silva L, Melendez ME, Cury F, Gomes I, Tansini A, Longato G, Martinho O, Oliveira BG, Pinto F, Romão W, Ribeiro R, Reis RM...

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Validation of a novel software tool for automatic aortic annular sizing in 3D transesophageal echocardiographic images

Queirós S, Morais P, Dubois C, Voigt J, Fonseca JC, Vilaça JL, D’hooge J. Validation of a novel software tool for automatic aortic annular sizing in 3D...

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STATs in lung development: distinct early and late expression, growth modulation and signaling dysregulation in congenital diaphragmatic hernia

Piairo P, Moura RS, Baptista MJ, Correia-Pinto J, Nogueira-Silva C. STATs in lung development: distinct early and late expression, growth modulation and...

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A novel multi-atlas strategy with dense deformation field reconstruction for abdominal and thoracic multi-organ segmentation from computed tomography

Oliveira B, Queirós S, Morais P, Torres HR, Gomes-Fonseca J, Fonseca JC, Vilaça JL. A novel multi-atlas strategy with dense deformation field reconstruction for...

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Video-Based Surgical Learning: Improving Trainee Education and Preparation for Surgery

Mota P, Carvalho N, Carvalho-Dias E, João Costa M, Correia-Pinto J, Lima E. Video-Based Surgical Learning: Improving Trainee Education and Preparation for...

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Prenatal microRNA miR-200b Therapy Improves Nitrofen-induced Pulmonary Hypoplasia Associated With Congenital Diaphragmatic Hernia

Khoshgoo N, Kholdebarin R, Pereira-Terra P, Mahood TH, Falk L, Day CA, Iwasiow BM, Zhu F, Mulhall D, Fraser C, Correia-Pinto J, Keijzer R. Prenatal microRNA...

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The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications

Gomes SD, Oliveira CS, Azevedo-Silva J, Casanova M, Barreto J, Pereira H, Chaves S, Rodrigues L, Casal M, Corte-Real M, Baltazar F, Preto A. The Role of Diet...

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Adenine derivatives: promising candidates for breast cancer treatment

Figueiredo P, Costa M, Pontes O, Baltazar F, Proença F. Adenine derivatives: promising candidates for breast cancer treatment. European Journal of Organic...

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Precut fistulotomy – widening its limits

Fernandes J, Libânio D, Giestas S, Ramada J, Martinez-Ares D, Canena J, Lopes L. Precut fistulotomy – widening its limits. Endoscopy...

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Giant symptomatic rectal lipoma resected by endoscopic submucosal dissection

Fernandes J, Libânio D, Giestas S, Araújo T, Martinez-Ares D, Certo M, Lopes L. Giant symptomatic rectal lipoma resected by endoscopic submucosal...

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Trend analysis of the quality indicators for the Brazilian cervical cancer screening programme by region and state from 2006 to 2013

Costa RFA, Longatto-Filho A, de Lima Vazquez F, Pinheiro C, Zeferino LC, Fregnani JHTG. Trend analysis of the quality indicators for the Brazilian cervical...

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Serological inflammatory factors as biomarkers for anatomic response in diabetic macular edema treated with anti-VEGF

Brito P, Costa J, Gomes N, Costa S, Correia-Pinto J, Silva R. Serological inflammatory factors as biomarkers for anatomic response in diabetic macular edema...

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In vivo assessment of a novel biodegradable ureteral stent

Barros AA, Oliveira C, Ribeiro AJ, Autorino R, Reis RL, Duarte ARC, Lima E. In vivo assessment of a novel biodegradable ureteral stent. World Journal of...

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The germline mutational landscape of BRCA1 and BRCA2 in Brazil

Barbara Alemar B, Palmero EI, Carraro DM, Moreira M, Ribeiro-dos-Santos A, Abe-Sandes K, Galvão H, Reis RM, Padua Souza C, Campacci N, Achatz MI, Brianese RC...

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A painful lesion on the abdomen

Veiga C, Leão P. A painful lesion on the abdomen. BMJ 357:j1823 (2017)

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Fully Automatic 3-D-TEE Segmentation for the Planning of Transcatheter Aortic Valve Implantation

Queirós S, Papachristidis A, Morais P, Theodoropoulos KC, Fonseca JC, Monaghan MJ, Vilaça JL, D’hooge J. Fully Automatic 3-D-TEE Segmentation for the...

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A competitive strategy for atrial and aortic tract segmentation based on deformable models

Morais P, Vilaça JL, Queirós S, Bourier F, Deisenhofer I, Tavares JMR, D’hooge J. A competitive strategy for atrial and aortic tract segmentation based on...

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HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors

Martinho O, Silva-Oliveira R, Cury FP, Barbosa AM, Granja S, Evangelista AF, Marques F, Miranda-Gonçalves V, Cardoso-Carneiro D, de Paula FE, Zanon M...

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Identification of miRSNPs associated with the risk of multiple myeloma

Macauda A, Calvetti D,(…) Marques H, (…) Reis RM, (…) Gemignani F, Canzian F. Identification of miRSNPs associated with the risk of multiple...

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Ureteroscopy-assisted Percutaneous Kidney Access Made Easy: First Clinical Experience with a Novel Navigation System Using Electromagnetic Guidance (IDEAL Stage 1)

Lima E, Rodrigues PL, Mota P, Carvalho N, Dias E, Correia-Pinto J, Autorino R, Vilaça JL. Ureteroscopy-assisted Percutaneous Kidney Access Made Easy: First Clinical...

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Integrated genomic characterization of oesophageal carcinoma

Kim J, Bowlby R,(…) Reis RM, (…) Sofia HJ, Zhang J. Integrated genomic characterization of oesophageal carcinoma. Nature 541(7636):169-175 (2017)

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Value of pH regulators in the diagnosis, prognosis and treatment of cancer

Granja S, Tavares-Valente D, Queirós O, Baltazar F. Value of pH regulators in the diagnosis, prognosis and treatment of cancer. Seminars in Cancer Biology...

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Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy

Ferreira NN, Ferreira LMB, Miranda-Gonçalves V, Reis RM, Seraphim TV, Borges JC, Baltazar F, Gremião MPD. Alginate hydrogel improves anti-angiogenic...

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SETDB2 and RIOX2 are differentially expressed among renal cell tumor subtypes, associating with prognosis and metastization

Ferreira MJ, Pires-Luís AS, Vieira-Coimbra M, Costa-Pinheiro P, Antunes L, Dias PC, Lobo F, Oliveira J, Gonçalves CS, Costa BM, Henrique R, Jerónimo C. SETDB2...

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Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells

Faião-Flores F, Alves-Fernandes DK, Pennacchi PC, Sandri S, Vicente AL, Scapulatempo-Neto C, Vazquez VL, Reis RM, Chauhan J, Goding CR, Smalley KS, Maria-Engler...

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A three-dimensional model of human lung development and disease from pluripotent stem cells

Chen YW, Huang SX, de Carvalho ALRT, Ho SH, Islam MN, Volpi S, Notarangelo LD, Ciancanelli M, Casanova JL, Bhattacharya J, Liang AF, Palermo LM, Porotto M...

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Loss of caveolin-1 in metastasis-associated macrophages drives lung metastatic growth through increased angiogenesis

Celus W, Di Conza G, Oliveira AI, Ehling M, Costa BM, Wenes M, Mazzone M. Loss of caveolin-1 in metastasis-associated macrophages drives lung metastatic...

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A semiautomated microfluidic platform for real-time investigation of nanoparticles’ cellular uptake and cancer cells’ tracking

Carvalho MR, Maia FR, Silva-Correia J, Costa BM, Reis RL, Oliveira JM. A semiautomated microfluidic platform for real-time investigation of nanoparticles’...

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Imaging Ischemic and Reperfusion Injury in Acute Myocardial Infarction: Putting the Pieces Together With CMR

Bogaert J, Curione D, Morais P, Barreiro-Perez M, Tilborghs S, Maes F, Dresselaers T. Imaging Ischemic and Reperfusion Injury in Acute Myocardial Infarction...

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Tumor Growth Suppression Induced by Biomimetic Silk Fibroin Hydrogels

Yan LP, Silva-Correia J, Ribeiro VP, Miranda-Goncalves V, Correia C, Morais AD, Sousa RA, Reis RM, Oliveira AL, Oliveira JM, Reis RL. Tumor Growth Suppression...

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Simulator training in gastrointestinal endoscopy – From basic training to advanced endoscopic procedures

van der Wiel SE, Küttner Magalhães R, Rocha Gonçalves CR, Dinis-Ribeiro M, Bruno MJ, Koch AD. Simulator training in gastrointestinal endoscopy – From basic...

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Prognostic significance of monocarboxylate transporter expression in oral cavity tumors

Simões-Sousa S, Granja S, Pinheiro C, Fernandes D, Longatto-Filho A, Laus AC, Alves CD, Suárez-Peñaranda JM, Pérez-Sayáns M, Lopes Carvalho A, Schmitt FC...

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Mechanisms of vertebrate embryo segmentation: Common themes in trunk and limb development

Sheeba CJ, Andrade RP, Palmeirim I. Mechanisms of vertebrate embryo segmentation: Common themes in trunk and limb development. Seminars in Cell &...

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Getting a handle on embryo limb development: Molecular interactions driving limb outgrowth and patterning

Sheeba CJ, Andrade RP, Palmeirim I. Getting a handle on embryo limb development: Molecular interactions driving limb outgrowth and patterning. Seminars in Cell...

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Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation

Sandri S, Faião-Flores F, Tiago M, Pennacchi PC, Massaro RR, Alves-Fernandes DK, Berardinelli GN, Evangelista AF, de Lima Vazquez V, Reis RM, Maria-Engler SS...

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A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis

Ríos-Tamayo R, Lupiañez CB, Campa D, Hielscher T, Weinhold N, Martínez-López J, Jerez A, Landi S, Jamroziak K, Dumontet C, Wątek M, Lesueur F, Reis RM, Marques...

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Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer

Pinto F, Pértega-Gomes N, Vizcaíno JR, Andrade RP, Cárcano FM, Reis RM. Brachyury as a potential modulator of androgen receptor activity and a key player in...

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The embryonic Brachyury transcription factor is a novel biomarker of GIST aggressiveness and poor survival

Pinto F, Campanella NC, Abrahão-Machado LF, Scapulatempo-Neto C, de Oliveira AD, Brito MJ, Andrade RP, Guimarães DP, Reis RM. The embryonic Brachyury...

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The metabolic microenvironment of melanomas: prognostic value of MCT1 and MCT4

Pinheiro C, Miranda-Gonçalves V, Longatto-Filho A, Vicente A, Noriz Berardinelli G, Scapulatempo C, Costa RA, Viana CR, Reis RM, Baltazar F, Vazquez V. The...

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Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas

Miranda-Gonçalves V, Granja S, Martinho O, Honavar M, Pojo M, Costa BM, Pires MM, Pinheiro C, Cordeiro M, Bebiano G, Costa P, Reis RM, Baltazar F...

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Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

Jezkova J, Williams JS, Pinto F, Sammut SJ, Williams GT, Gollins S, McFarlane RJ, Reis RM, Wakeman JA. Brachyury identifies a class of enteroendocrine cells...

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The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients’ survival

Fogli A, Chautard E, Vaurs-Barrière C, Pereira B, Müller-Barthélémy M, Court F, Biau J, Pinto AA, Kémény JL, Khalil T, Karayan-Tapon L, Verrelle P, Costa BM...

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revalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry

Fernandes GC, Michelli RA, Galvão HC, Paula AE, Pereira R, Andrade CE, Felicio PS, Souza CP, Mendes DR, Volc S, Berardinelli GN, Grasel RS, Sabato CS, Viana DV, Mauad...

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Biological importance of structurally diversified chromenes

Costa M, Dias TA, Brito A, Proença F. Biological importance of structurally diversified chromenes. European Journal of Medicinal Chemistry...

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Understanding TERT Promoter Mutations: a Common Path to Immortality

Bell RJA, Rube HT, Xavier-Magalhães A, Costa BM, Mancini A, Song JS, Costello JF. Understanding TERT Promoter Mutations: a Common Path to...

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The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism

Batista R, Cruvinel-Carloni A, Vinagre J, Peixoto J, Catarino TA, Campanella NC, Menezes W, Becker AP, Caravina GA, Matsushita MM, Clara C, Neder...

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Drug-eluting biodegradable ureteral stent: New approach for urothelial tumors of upper urinary tract cancer

Barros AA, Browne S, Oliveira C, Lima E, Duarte AR, Healy KE, Reis RL. Drug-eluting biodegradable ureteral stent: New approach for urothelial tumors of upper...

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Histone methyltransferase PRMT6 plays an oncogenic role in prostate cancer

Almeida-Rios D, Graça I, Vieira FQ, Ramalho-Carvalho J, Pereira-Silva E, Martins AT, Oliveira J, Gonçalves CS, Costa BM, Henrique R, Jerónimo C. Histone...

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Metabolic coupling in urothelial bladder cancer compartments and its correlation to tumour aggressiveness.

Afonso J, Santos LL, Morais A, Amaro T, Longatto-Filho A, Baltazar F. Metabolic coupling in urothelial bladder cancer compartments and its correlation to...

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Micro- and Mesoporous Structures as Drug Delivery Carriers for Salicylic Acid

Vilaça N, Morais-Santos F, Machado AF, Sirkeciogl̆u A, Pereira MFR, Sardo M, Rocha J, Parpot P, Fonseca AM, Baltazar F, Neves IC. Micro- and Mesoporous...

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SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3

Vieira FQ, Costa-Pinheiro P, Almeida-Rios D, Graça I, Monteiro-Reis S, Simões-Sousa S, Carneiro I, Sousa EJ, Godinho MI, Baltazar F, Henrique R, Jerónimo C...

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Getting a handle on embryo limb development: Molecular interactions driving limb outgrowth and patterning

Sheeba CJ, Andrade RP, Palmeirim I. Getting a handle on embryo limb development: Molecular interactions driving limb outgrowth and patterning. Seminars in Cell...

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Type 2 diabetes-related variants influence the risk of developing Multiple Myeloma

Ríos R, Lupiañez CB, Campa D, Martino A, Martínez-López J, Varkonyi J, García-Sanz R, Jamroziak K, Dumontet C, Cayuela AJ, Wątek M, Landi S, Rossi AM, Lesueur...

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Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication

Pires-Luís AS, Vieira-Coimbra M, Vieira FQ, Costa-Pinheiro P, Silva-Santos R, Dias PC, Antunes L, Lobo F, Oliveira J, Gonçalves CS, Costa BM, Henrique R...

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Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors

Pinheiro C, Granja S, Longatto-Filho A, Faria AM, Fragoso MC, Lovisolo SM, Lerário AM, Almeida MQ, Baltazar F, Zerbini MC. Metabolic reprogramming: a new relevant...

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A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: A role for Monocarboxylate Transporters as metabolic targets for therapy

Pértega-Gomes N, Felisbino S, Massie C, Vizcaíno JR, Coelho R, Sandi C, Sousa S, Jurmeister S, Ramos-Montoya A, Asim M, Tran M, Oliveira E, Lobo da Cunha A, Maximo...

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Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplastic lung development

Pereira-Terra P, Moura RS, Nogueira-Silva C, Correia-Pinto J. Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplastic lung...

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Unique Tracheal Fluid MicroRNA Signature Predicts Response to FETO in Patients with Congenital Diaphragmatic Hernia

Pereira-Terra P, Deprest JA, Kholdebarin R, Khoshgoo N, Dekoninck P, Boerema-De Munck AA, Wang J, Zhu F, Rottier RJ, Iwasiow BM, Correia-Pinto J, Tibboel D, Post...

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Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria

Oliveira C.S.F., Pereira H, Alves S, Castro L, Baltazar F, Chaves SR, Preto A, Côrte-Real M. Cathepsin D protects colorectal cancer cells from acetate-induced...

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Targeting lactate transport suppresses in vivo breast tumour growth

Morais-Santos F, Sara Granja, Vera Miranda-Gonçalves, António H.J. Moreira, Sandro Queirós, João L. Vilaça, Fernando C. Schmitt, Adhemar Longatto-Filho, Joana...

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Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction

Marchiq I, Albrengues J, Granja S, Gaggioli C, Pouysségur J, Simon MP. Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour...

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Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status

Granja S, Marchiq I, Le Floch E, Souto-Moura C, Baltazar F, Pouyssegur J. Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung...

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Patterning in time and space: HoxB cluster gene expression in the developing chick embryo

Gouveia A, Marcelino HM, Gonçalves L, Palmeirim I, Andrade RP. Patterning in time and space: HoxB cluster gene expression in the developing chick...

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Ectopic varices in a pancreatojejunal anastomosis: a rare cause of hemorrhage

Gonçalves BM, Bastos P, Leão P, Rolanda C. Ectopic varices in a pancreatojejunal anastomosis: a rare cause of hemorrhage. Endoscopy 47:E269-E270 (2015)

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MET is required for the recruitment of anti-tumoural neutrophils

Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson R, Wauters E, Walmsley S, Prenen H, Granot Z, Casazza A, Mazzone M. MET is required for the...

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MicroRNA-375 plays a dual role in prostate carcinogenesis

Costa-Pinheiro P, Ramalho-Carvalho J, Vieira FQ, Torres-Ferreira J, Oliveira J, Gonçalves CS, Costa BM, Henrique R, Jerónimo C. MicroRNA-375 plays a dual role in...

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Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length

Campa D, Martino A, Varkonyi J, Lesueur F, Jamroziak K, Landi S, Jurczyszyn A, Marques H, Andersen V, Jurado M, Brenner H, Petrini M, Vogel U, García-Sanz R, Buda G...

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Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells

Amorim R, Pinheiro C, Miranda-Gonçalves V, Pereira H, Moyer M, Preto A, Baltazar F. Monocarboxylate transport inhibition potentiates the cytotoxic effect of...

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CD147 and MCT1 – Potential partners in bladder cancer aggressiveness and cisplatin resistance

Afonso J, Santos LL, Miranda-Gonçalves V, Morais A, Amaro T, Longatto-Filho A, Baltazar F. CD147 and MCT1 – Potential partners in bladder cancer aggressiveness and...

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Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, Borlido J, Stark R, Ireland-Zecchini H, Rao R, Scott H, Boren J, Massie C, Asim M, Brindle K...

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The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype

Sousa B, Ribeiro AS, Nobre AR, Lopes N, Martins D, Pinheiro C, Vieira AF, Albergaria A, Gerhard R, Schmitt F, Baltazar F, Paredes J. The basal epithelial...

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Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models

Silva-Carvalho R, Miranda-Goncalves V, Ferreira AM, Cardoso SM, Sobral AJFN, Almeida-Aguiar C, Baltazar F. Antitumoural and antiangiogenic activity of Portuguese...

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Limb patterning: from signalling gradients to molecular oscillations

Sheeba CJ, Andrade RP, Palmeirim I. Limb patterning: from signalling gradients to molecular oscillations. Journal of Molecular Biology...

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Fast Automatic Myocardial Segmentation in 4D cine CMR datasets

Queirós S, Barbosa D, Heyde B, Morais P, Vilaça JL, Friboulet D, Bernard O, D’hooge J. Fast Automatic Myocardial Segmentation in 4D cine CMR...

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T-box transcription factor Brachyury is associated with prostate cancer progression and aggressiveness

Pinto F, Pértega-Gomes N, Pereira MS, Vizcaíno JR, Monteiro P, Henrique RM, Baltazar F, Andrade RP, Reis RM. T-box transcription factor Brachyury is associated...

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Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: Distinct prognostic impact of MCT1 sub-cellular localization

Pinheiro C, Penna V, Morais-Santos F, Abrahão-Machado L, Ribeiro G, Curcelli EC, Olivieri MV, Morini S, Valença I, Ribeiro D, Schmitt FC, Reis RM, Baltazar...

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Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix

Pinheiro C, Garcia EA, Morais-Santos F, Scapulatempo-Neto C, Mafra A, Stenbergen R, Boccardo E, Villa LL, Baltazar F, Longatto-Filho A. Lactate transporters...

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A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer

Pértega-Gomes N, Vizcaíno JR, Attig J, Jurmeister S, Lopes C, Baltazar F. A lactate shuttle system between tumour and stromal cells is associated with poor...

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Canonical Wnt Signaling Activity in Early Stages of Chick Lung Development

Moura R, Carvalho-Correia E, da Mota P, Correia- Pinto J. Canonical Wnt Signaling Activity in Early Stages of Chick Lung Development. PLOS One...

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Hybrid Endoscopic Thymectomy: combined transesophageal and transthoracic approach in a survival porcine model with cadaver assessment

Moreira-Pinto J, Ferreira A, Miranda A, Rolanda C, Correia-Pinto J. Hybrid Endoscopic Thymectomy: combined transesophageal and transthoracic approach in a survival...

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Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations -An Extensive Replication of the Associations from the Candidate Gene Era

Martino A, Campa D, Jurczyszyn A, Martínez-López, la Fuente, Varkonyi J, Dumontet C, García-Sanz R, Gemignani F, Jamroziak K, Jurado M, Landi S, Rossi AM, Lesueur F...

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MicroRNA expression as risk biomarker of breast cancer metastasis: a pilot retrospective case-cohort study

Marino AL, Evangelista AF, Vieira RA, Macedo T, Kerr LM, Abrahão-Machado LF, Longatto-Filho A, Silveira HC, Marques MM. MicroRNA expression as risk biomarker of...

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Early precut fistulotomy for biliary access: time to change the paradigm of “the later the better”?

Lopes L, Dinis-Ribeiro M, Rolanda C. Early precut fistulotomy for biliary access: time to change the paradigm of “the later the better”? Gastrointestinal...

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Congenital duodenal obstruction and double-bubble sign

Correia-Pinto J, Ribeiro A. Congenital duodenal obstruction and double-bubble sign. The New England Journal of Medicine 371(11):E16 (2014)

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Results of the European Basic Laparoscopic Urological Skills Examination

Autorino R, Cicione A, Rassweiler J, Lima E. Re: Willem M. Brinkman, Irene M. Tjiam, Barbara M. A. Schout, et al. Results of the European Basic Laparoscopic...

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Limb patterning: from signalling gradients to molecular oscillations

Sheeba CJ, Andrade RP, Palmeirim I. Limb patterning: from signalling gradients to molecular oscillations. Journal of Molecular Biology...

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Collecting system percutaneous access using real-time tracking sensors: first pig model in vivo experience

Rodrigues PL, Vilaça JL, Oliveira C, Cicione A, Rassweiler J, Fonseca J, Rodrigues NF, Correia-Pinto J, Lima E. Collecting system percutaneous access using...

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Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate cancer

Pértega-Gomes N, Vizcaíno JR, Gouveia C, Jerónimo C, Henrique RM, Lopes C, Baltazar F. Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate...

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The role of glycoprotein 130 family of cytokines in fetal rat lung development

Nogueira-Silva C, Piairo P, Carvalho-Dias E, Veiga C, Moura RS, Correia-Pinto J. The role of glycoprotein 130 family of cytokines in fetal rat lung...

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Bladder Endometriosis: a Diagnostic Challenge

Nogueira-Silva C, Leitão TP, Osório F. Bladder Endometriosis: a Diagnostic Challenge. BMJ 346:f3513 (2013)

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Differential sensitivities to lactate transport inhibitors of breast cancer cell lines

Morais-Santos F, Miranda-Gonçalves V, Pinheiro S, Vieira AF, Paredes J, Schmitt F, Baltazar F, Pinheiro C. Differential sensitivities to lactate transport...

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Loss of caveolin-1 and gain of MCT4 expression in the tumor stroma: Key events in the progression from an in situ to an invasive breast carcinoma

Martins D, Beça FF, Sousa B, Baltazar F, Paredes J, Schmitt F. Loss of caveolin-1 and gain of MCT4 expression in the tumor stroma: Key events in the progression...

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PHD2 regulates arteriogenic macrophages through TIE2 signaling

Hamm A, Veschini L, Takeda Y, Costa S, Delamarre E, Squadrito ML, Henze A-T, Wenes M, Serneels J, Pucci F, Roncal C, Anisimov A, Alitalo K, DePalma M, Mazzone M...

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The monocarboxylate transporter inhibitor α-cyano-4-hydroxycinnamic acid disrupts rat lung branching

Granja S, Morais-Santos F, Miranda-Gonçalves V, Viana-Ferreira M, Nogueira R, Nogueira-Silva C, Correia-Pinto J, Baltazar F. The monocarboxylate transporter inhibitor...

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